Open Positions

In addition to the formal positions listed below, we are always interested in hearing from motivated applicants at

Visit the Projects page to learn more about our work and appropriate contacts.

Master’s/Bachelor’s Student Research Positions
Laboratory & Computational Biophysics of Ion Channels

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Three types of Research/Degree Projects are currently available in the ligand-gated ion channels group, headed by Prof Erik Lindahl. Under the supervision of Dr Reba Howard, students will focus on laboratory or computational biophysics approaches to investigate the structure and function of proteins involved in cellular regulation and signaling, particularly the activation and modulation of ion channels.

Applicants should have some theoretical and/or laboratory preparation in biophysics, biochemistry, or related fields at the Bachelor’s or Master’s levels, and an enthusiasm for interdisciplinary research and communication. Contact for further details.

Project 1—Electrophysiology of Novel Receptor Variants
Express and characterize ion channel proteins in a model cell system, using molecular biology and voltage-clamp recordings to quantify expression, gating, and modulation towards structure determination and/or drug development.

Project 2—Simulating Ion Channel Gating and Modulation
Harness recent structure-function data to simulate and analyze ion channel models, using methods such as molecular dynamics and docking to probe structural changes, drug binding, and/or novel mutations.

Project 3—Methods Development in Cryo-Electron Microscopy
Optimize sample preparation, data collection, and/or image analysis to elucidate the atomic structure of technically challenging macromolecules, focusing on biochemistry or software methods in cryo-electron microscopy.