Emelia Karlsson

PhD Student
Department of Biochemistry & Biophysics
Stockholm University

Email: emelia.karlsson@scilifelab.se

Team: Integrative Structural Biology

Emelia’s work aims to contribute new insight into receptor allostery and synaptic transmission by targeting a vital family of ion channels in our nervous system, expressly, pentameric ligand-gated ion channels (pLGICs). Her research is investigating how structure-function relationships may alter the mechanics of gating and allosteric modulation by noncanonical modulators, including pH, Ca2+ and stimulants, among prokaryotic and eukaryotic members of the pLGIC family. Quantifying modulation will primarily be accomplished by two-electrode voltage-clamp in Xenopus laevis oocytes and analyzing single ion channel behavior by a new technique for lipid bilayer recordings she established in the lab, complemented with structural and simulation data.

Master’s Program in Molecular Biotechnology Engineering (Applied Biophysics profile), Uppsala University (2022)

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