Dari Kimanius

PhD Student
Department of Biochemistry & Biophysics
Stockholm University

Email: dkimanius@gmail.com
Projects: Cryo-electron microscopy

Dari is mainly  focused on method development  in Cryo-EM data refinement. He’s been developing the popular refinement software package RELION for the past three years and applied much of these new tools for structural determination of human ribosomal intermediates.

Online

Background

  • Since 2014: PhD in Bioinformatics, Stockholm University, Sweden
  • 2010-2014: Civil Engineering Degree, Engineering Physics, KTH, Sweden.
  • 2009-2010: M.D. Karolinska Institue, Sweden
  • 2017: International HPC Summer School 2017, Boulder, Colorado

Selected Publications

  • Kimanius, D., Forsberg, B.O., Scheres, S.H. and Lindahl, E., 2016. Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2. Elife5.
  • Kimanius D, Pettersson I, Schluckebier G, Lindahl E, Andersson M. SAXS-guided metadynamics. Journal of chemical theory and computation. 2015 Jun 25;11(7):3491-8.
  • Brown A, Rathore S, Kimanius D, Aibara S, Bai XC, Rorbach J, Amunts A, Ramakrishnan V. Structures of the human mitochondrial ribosome in native states of assembly. Nature Structural and Molecular Biology. 2017 Oct;24(10):866.
  • Boerema AP, Aibara S, Paul B, Tobiasson V, Kimanius D, Forsberg BO, Wallden K, Lindahl E, Amunts A. Structure of the chloroplast ribosome with chl-RRF and hibernation-promoting factor. Nature plants. 2018 Apr;4(4):212.
  • Nakane T, Kimanius D, Lindahl E, Scheres SH. Characterisation of molecular motions in cryo-EM single-particle data by multi-body refinement in RELION. bioRxiv. 2018 Jan 1:286856.